What is Vonvendi®?

Created specifically for von Willebrand disease (VWD) bleeding episodes1

VONVENDI is the first and only recombinant treatment for adults with VWD.2 It helps control bleeds both on-demand and prevent excessive bleeding in surgery.1

VONVENDI® container and glass bottles.

Key facts about VONVENDI

VONVENDI® is made without human blood or plasma.

Manufactured without human blood or plasma

VONVENDI is recombinant, meaning it's made without using human blood. This technology avoids the risk of spreading diseases through infected human blood.3

VONVENDI® can be used with or without recombinant FVIII as directed.

Can be used with or without recombinant FVIII as directed

Depending on your specific situation, your healthcare provider will decide if you may use VONVENDI by itself, or if you require additional recombinant FVIII (rFVIII).1

Approved for two separate uses

Your healthcare provider may prescribe VONVENDI for two different uses: on-demand treatment of bleeds and to prevent excessive bleeding during and after surgery.1

Bleeding finger icon.

On-demand

VONVENDI can be used on-demand by adults with VWD to control major and minor bleeds in all locations, including mouth bleeds, nosebleeds, heavy menstrual bleeds, GI bleeds, and joint bleeds.1

Learn about using VONVENDI on-demand
Doctor performing surgery on a patient icon.

For surgery

VONVENDI can be used to prevent excessive bleeding during and after surgical procedures, such as tooth extractions and colonoscopies.1

Learn about VONVENDI for surgery

How VONVENDI works

VONVENDI is infused into your blood stream, where it acts like your body's natural von Willebrand factor (VWF), helping to form clots, and helping your own FVIII to work.1

White and red blood cells.
Doctor talking to her VWD patient.

VONVENDI® side effects

Always talk to your healthcare provider before taking any prescription medication, including VONVENDI. Learn more about VONVENDI side effects and safety.

See safety info
Real VWD patient, Erica standing next to some flowers and smiling. VONVENDI® can be used for on-demand treatment.
On-demand efficacy

A clinical trial tested VONVENDI in adults for on-demand use.1

Get the stats
Doctor talking about VONVENDI® for surgical use.
Surgical use efficacy

A clinical trial tested VONVENDI in adults
with VWD undergoing surgery.1

Learn more

References

  1. VONVENDI Prescribing Information
  2. Baxalta receives FDA Approval for VONVENDI, the first and only recombinant treatment for adults affected by von Willebrand disease. Business Wire. December 8, 2015. Accessed July 9, 2020. https://www.businesswire.com/news/home/20151208006689/en/Baxalta-Receives-FDA-Approval-VONVENDIRecombinant-Treatment
  3. Franchini M, Mannucci PM. Von Willebrand factor (Vonvendi®): the first recombinant product licensed for the treatment of von Willebrand disease. Expert Rev Hematol. 2016;9(9):825-830.
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