Prophylaxis Treatment

With VONVENDI® prophylaxis, you may be able to protect against frequent bleeds before they even occur.1

In a clinical trial, routine prophylaxis with VONVENDI helped reduce the number of bleeds for adults with severe Type 3 von Willebrand Disease (VWD) who were previously treated on-demand.

VONVENDI® patient taking notes.

What is prophylaxis, or "prophy"?

Prophylaxis treatment is taken routinely to reduce the number of bleeds rather than waiting for a bleed to happen and treating it on demand. VONVENDI was tested in a clinical trial for prophylaxis treatment.1

VONVENDI prophylaxis reduced the number of bleeds in adults with severe Type 3 VWD1

VONVENDI® average number of bleeds calendar icon.

Annualized bleed rate (ABR) is a common term/abbreviation used when talking about the average number of bleeds a person with a bleeding disorder experiences in a year.2

Median ABR refers to the middle value in a sorted list of annual bleeds.

Trial Description

Routine prophylaxis with VONVENDI was studied over the course of a year in 10 adults with severe Type 3 VWD who had previously received on-demand treatment (Prior OD). During the study, the majority of patients (9/10) received twice-weekly dosing with VONVENDI.1 The median ABRs were compared for the 12 months during the study (on-study) against the 12 months prior to the study (historical).1

With VONVENDI prophylaxis, you may be able to
protect against bleeds before they even occur1

VONVENDI can be used on a twice-weekly routine by adults with severe Type 3 VWD
receiving on-demand therapy to reduce the frequency of bleeding episodes.1

Calendar icon showing VONVENDI® twice a week schedule.

2x weekly dosing

In a clinical trial, routine prophylaxis with VONVENDI helped reduce the number of bleeds for adults with severe Type 3 von Willebrand Disease (VWD) who were previously treated on-demand.

Is prophylaxis right for you?

Our easy-to-use Discussion Guide, used alongside our bleed tracker, can help you speak to your healthcare provider to see if VONVENDI prophylaxis might be right for you.

Download the guide
Doctor discussion guide brochure.
Real VWD patient, Erica standing next to some flowers and smiling. VONVENDI® can be used for on-demand treatment.
On-demand efficacy

A clinical trial tested VONVENDI in adults for on-demand use.1

Get the stats
Doctor talking about VONVENDI® for surgical use.
Surgical use efficacy

A clinical trial tested VONVENDI in adults
with VWD undergoing surgery.1

Learn more
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