VONVENDI^® and surgery

In a clinical trial, 100% of adult VWD patients had their surgical bleeding successfully managed with VONVENDI.

style

Alternate, Rounded Flush, Mobile Reverse, Neutral subtle

Study description

VONVENDI, given with or without additional recombinant factor VIII (rFVIII), was studied in a clinical trial to test how it would work to prevent excessive bleeding during and after surgery. The clinical trial included 15 adult patients who underwent a total of 15 surgeries.

In this trial, patients received VONVENDI before and after surgery as determined by the care team. rFVIII was given as needed.* Investigators rated bleed control on a 4-point scale where “Excellent”=1, “Good”=2, “Moderate”=3, and “None”=4. A rating of “Excellent” or “Good” was required to declare the outcome a success.

style

Center, Content Width XL

100% of adult surgeries (15 of 15) were managed successfully, with 9/15 rated as “Excellent” and 6/15 rated as “Good”

The amount of blood loss experienced by people in the study was comparable to that of a person without VWD

Most people (10/15) needed only VONVENDI to manage their surgical bleeding

Study safety

Six patients reported 12 adverse events after starting treatment. One case of a blood clot in a deep vein, also known as deep vein thrombosis (DVT), was considered possibly related to VONVENDI.

*Your doctor will decide if you may use VONVENDI by itself, or if you also require rFVIII along with VONVENDI, based on your clinical situation.

style

Center, Content Width XL

Bleed control for a range of procedures

VONVENDI can be used to prevent excessive bleeding during and after major and minor surgeries and procedures in various locations, including:

Mouth
(eg, dental extraction)

Nose/throat
(eg, nasopharyngoscopy)

Female reproductive system
(eg, cyst removal)

GI tract
(eg, colonoscopy)

Joint
(eg, joint replacement)

style

Tertiary Secondary Horizontal, Center

Leslie’s Story

Diagnosed with VWD in 2003

"Once I was trained on how to do my own infusion, I infused on the eve of the surgery and again right before. I also infused after surgery—this was my normal for any surgery. I was amazed at how well this treatment worked for me."

See her story

Erica’s Story

Diagnosed with VWD in 1981

"I feel fortunate that there's been an increase in awareness when it comes to VWD, from diagnosis and available information to patient care."

See her story

Nicole's Story

Diagnosed with VWD in 2009

"Although I've faced many battles since I was diagnosed, the amount of support I had from all the other patients fighting the same battle gave me strength."

See her story