To ensure the powder is completely dissolved, swirl the connected vials gently and continuously or allow the reconstituted product to sit for 5 minutes then gently swirl (Figure E). Do not shake. Shaking will adversely affect the product.

Note: Some flakes or particles may remain in the reconstituted vial. The filter included in the Mix2Vial device will remove extraneous flakes or particles, and the resulting solution in the syringe should be clear and colorless. Do not use the solution in the syringe if it is cloudy or contains flakes or particles after filtration from the vial into the syringe.

Hand swirling the vials on top of each other.

Disconnect the two sides of the Mix2Vial device from each other by turning the blue plastic side of the Mix2Vial counterclockwise and gently pulling the two vials apart (Figure F). Do not touch the end of the plastic connector attached to the VONVENDI vial containing the dissolved product.
Discard empty diluent vial and the blue part of the Mix2Vial.

Hands disconnecting the two Mix2Vials. Do not touch exposed connector.

NOTE: The Mix2Vial is intended for one-time use with a single vial of VONVENDI and diluent only. If the dose requires more than one vial of VONVENDI, reconstitute each vial using a separate Mix2Vial device. Do not refrigerate after reconstitution. Repeat reconstitution steps above for all VONVENDI product vials needed for your dose prior to continuing on to the next step.